Epitalon
Also known as: AEDG, Epithalon, Ala-Glu-Asp-Gly
Synthetic pineal tetrapeptide (AEDG) studied as a geroprotector: upregulates telomerase and helps restore melatonin rhythm and circadian timing. Evidence is largely from Russian research.
Pharmacokinetics
Research only · no verified human PK. The values below are class estimates, not measured data, and this peptide is excluded from the Lab serum-level simulator.
- Half-life
- 30 min
- Time to peak
- 15 min
- Bioavailability
- 80%
- Dosing interval
- 24h
Administration
- Primary routes
- SubQ, Intranasal
- Category
- Longevity & Anti-Aging
Safety Flags
- High immunogenicity
- Contraindicated in cancer history
Storage
- · Requires refrigeration (2–8°C)
- · Temperature sensitive — minimise room-temp exposure
Used in 2 outcome protocols
- Cellular RepairPrimary
Activate telomerase and support cellular longevity mechanisms
Safe default: 1mg · daily (10-20 day course, twice/year) · SubQ
- Sleep QualityPrimary
Improve sleep architecture and quality of rest
Safe default: 1mg · daily (10-20 day course, twice/year) · SubQ
Simulate Epitalon
Pinned.life runs a 1-compartment Bateman pharmacokinetic simulation against 38 peptides in real time. Build a stack, see serum-level curves, get warned about peak overlaps and drug-peptide interactions.