Longevity & Anti-Aging

FOX04-DRI

Also known as: FOXO4-DRI, Proxofim, FOXO4-D-Retro-Inverso

Senolytic peptide that disrupts the FOXO4-p53 interaction to selectively clear senescent (worn-out) cells. Animal evidence only, no human trials yet. Excluded from the PK simulator because no verified human data exists.

Pharmacokinetics

Research only · no verified human PK. The values below are class estimates, not measured data, and this peptide is excluded from the Lab serum-level simulator.
Half-life
3 days
Time to peak
4 hours
Bioavailability
70%
Onset
24 hours
Dosing interval
48h

Administration

Primary routes
SubQ
Category
Longevity & Anti-Aging

Safety Flags

  • Contraindicated in cancer history

Storage

  • · Requires refrigeration (2–8°C)
  • · Temperature sensitive — minimise room-temp exposure

Used in 1 outcome protocol

Simulate FOX04-DRI

Pinned.life runs a 1-compartment Bateman pharmacokinetic simulation against 38 peptides in real time. Build a stack, see serum-level curves, get warned about peak overlaps and drug-peptide interactions.